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TERANODE XDA Solutions
Customer Testimonials
Company
Worldwide Pharmaceutical
One the world's leading pharmaceutical companies focused on the development and commercialization of drugs to combat disease.
Challenges
Biological modeling and simulation was performed using mathematical formats, limiting reuse and communication.

Solution
TERANODE Design Suite integrated graphical and mathematical modeling and simulation, providing a standard, visual modeling platform to facilitate use across discovery and clinical research.
Results
Accelerated modeling biological systems:
  • Drives model development through graphical design instead of text-based mathematics
  • Reduces model formulation errors by automatically generating mathematics and simulation code
  • Provides electronic annotation capability
  • Improves communication between computational, discovery and clinical researchers
  • Integrates model, simulation and data analysis in one platform
PROJECT BACKGROUND
Prior to bringing in the TERANODE Design Suite, modeling and simulation of biological systems at this leading pharmaceutical company was supported with mathematical engineering software. These tools were unable to graphically model biological systems, hindering the communication and collaboration between computational biologists and other research scientists at the company. Because of this, The company utilized standard office software, like PowerPoint as a communication mechanism, to graphically depict the biological system being simulated.

ORGANIZATIONAL CHALLENGES
The need for cross-departmental communication and collaboration between the company's computational biologists and other research scientists has become increasingly important. The speed of that communication now has a direct impact on the company's bottom line. The company needed a tool that streamlined that communication and therefore accelerated the company's ability to apply the biological models and simulations in the laboratory.

Key purchase decision factors for the company were integrated graphical and mathematical modeling; the TERANODE Model server for model archiving; low cost relative to other providers.

TERANODE SOLUTION
The TERANODE Design Suite was brought in to provide computational biologists a platform that integrates graphical modeling, mathematical modeling, and biological simulation. It allows experimental scientists to communicate easily with modeling experts by directly annotating the working models with their observations and data. Models created using the Biological Modeler are now archived and shared across the collaborating groups, through the use of the TERANODE Model Server. The TERANODE Model Server allows organized check-in/check-out for model building and re-use.

Utilizing TERANODE Design Suite as a design automation platform for both the research and IT teams has delivered a standard interface to model and simulate biological systems. The biological modeling and simulation solution consists of the TERANODE Design Suite and the TERANODE Model Server running on an Oracle 9i Server.

Training and deployment times of the TERANODE solution took less than a week. Computational biologists were trained on the TERANODE Design Suite use at the basic level in under 4 hours. Advanced modeling and simulation by professional users required an additional 8 hours. Database support by IT professionals required less than 4 hours.

RESULTS
  • Drives model development through graphical design instead of text-based mathematics
  • Reduces model formulation errors by automatically generating mathematics and simulation code
  • Provides electronic annotation to models
  • Improves communication between computational, discovery and clinical researchers
  • Integrates model, simulation and data analysis in one platform
"The TERANODE Design Suite provides a modeling and simulation platform that strengthens our computational research activities, while providing biological models that can be leveraged across other discovery and clinical research groups."
Principal Scientist Leading Pharmaceutical Company